New Delhi amongst top cities where hearing is most degraded

March 5, 2017

Washington D.C, Mar 5: Urban noise pollution and hearing loss are closely linked, according to rankings of 50 large cities in both categories released on Friday.cars

High-decibel urban areas-such as Guangzhou, New Delhi, Cairo and Istanbul-topped the list of cities where hearing was most degraded, researchers reported.

Likewise, cities least afflicted by noise pollution-including Zurich, Vienna, Oslo and Munich-registered the lowest levels of decline in hearing.

This statistical link does not necessarily mean the constant din of city life is the main driver of hearing loss, which can also be caused by infections, genetic disorders, premature birth, and even some medicines.

The findings are also preliminary, and have yet to be submitted for peer-reviewed publication.

"But this is a robust result," said Henrik Matthies, managing director of Mimi Hearing Technologies, a German company that has amassed data on 200,000 people drawn from a hearing test administered via cell phones.

"The fact that noise pollution and hearing loss have such a tight correlation points to an intricate relationship," he told AFP.

Researchers at Mimi and Charite University Hospital in Berlin explored the link by constructing two separate databases.

The first combined information from the World Health Organization (WHO) and Norwegian-based technology research group SINTEF to create a noise pollution ranking for cities around the world.

Stockholm, Seoul, Amsterdam and Stuttgart were also among the least likely to assault one's ears, while Shanghai, Hong Kong and Barcelona came out as big noise makers.

Paris-one of the most densely populated major cities in Europe-scored as the third most cacophonous.

The ranking for hearing loss drew from Mimi's phone-based test, in which respondents indicated age and sex. Geo-location technology pinpointed the cities.

The results were measured against a standard for age-adjusted hearing.

On average, people in the loudest cities were ten years "older"-in terms of hearing loss-than those in the quietest cities, the study found.

Stacked side-by-side, the two city rankings are remarkably similar, suggesting more than an incidental link.

The findings highlight the need for better monitoring, the researchers said.

"While eye and sight checks are routine, ear and hearing exams are not," said Manfred Gross, head of the department of Audiology and Phoniatrics at Charite University Hospital.

"The earlier hearing loss is detected, the better the chances are for preventing further damage."

Collaborations between scientists and private companies that collect health-related information from consumers are becoming more common in the era of Big Data.

California-based DNA genetic testing company 23andMe, for example, has worked extensively with university researchers to ferret out rare genetic disorders by combing through mountains of anonymous data from its clients.

Also on Friday, World Hearing Day, the WHO released figures showing annual costs of unaddressed hearing loss of between $750 billion and $790 billion globally.

Direct health care costs were calculated to be up to $107 billion, with loss of productivity due to unemployment or early retirement about the same.

"Societal costs"-stemming from social isolation, inability to communicate and stigma-were estimated at more than $500 billion.

In a recent editorial, the medical journal The Lancet said hearing loss is a "silent epidemic", noting that proper care remains out of reach for millions of people.

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Agencies
March 3,2020

Taking multiple courses of antibiotics within a short span of time may do people more harm than good, suggests new research which discovered an association between the number of prescriptions for antibiotics and a higher risk of hospital admissions.

Patients who have had 9 or more antibiotic prescriptions for common infections in the previous three years are 2.26 times more likely to go to hospital with another infection in three or more months, said the researchers.

Patients who had two antibiotic prescriptions were 1.23 times more likely, patients who had three to four prescriptions 1.33 times more likely and patients who had five to eight 1.77 times more likely to go to hospital with another infection.

"We don't know why this is, but overuse of antibiotics might kill the good bacteria in the gut (microbiota) and make us more susceptible to infections, for example," said Professor Tjeerd van Staa from the University of Manchester in Britain.

The study, published in the journal BMC Medicine, is based on the data of two million patients in England and Wales.

The patient records, from 2000 to 2016, covered common infections such as upper respiratory tract, urinary tract, ear and chest infections and excluded long term conditions such as cystic fibrosis and chronic lung disease.

The risks of going to hospital with another infection were related to the number of the antibiotic prescriptions in the previous three years.

A course is defined by the team as being given over a period of one or two weeks.

"GPs (general physicians) care about their patients, and over recent years have worked hard to reduce the prescribing of antibiotics,""Staa said.

"But it is clear GPs do not have the tools to prescribe antibiotics effectively for common infections, especially when patients already have previously used antibiotics.

"They may prescribe numerous courses of antibiotics over several years, which according to our study increases the risk of a more serious infection. That in turn, we show, is linked to hospital admissions," Staa added.

It not clear why hospital admissions are linked to higher prescriptions and research is needed to show what or if any biological factors exist, said the research team.

"Our hope is that, however, a tool we are working for GPs, based on patient history, will be able to calculate the risks associated with taking multiple courses of antibiotics," said Francine Jury from the University of Manchester.

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Agencies
July 7,2020

The World Health Organization (WHO) is reviewing a report that suggested its advice on the novel coronavirus needs updating after some scientists told the New York Times there was evidence the virus could be spread by tiny particles in the air.

The WHO says the Covid-19 disease spreads primarily through small droplets, which are expelled from the nose and mouth when an infected person breaths them out in coughs, sneezes, speech or laughter and quickly sink to the ground.

In an open letter to the Geneva-based agency, 239 scientists in 32 countries outlined the evidence they say shows that smaller exhaled particles can infect people who inhale them, the newspaper said on Saturday.

Because those smaller particles can linger in the air longer, the scientists - who plan to publish their findings in a scientific journal this week - are urging WHO to update its guidance, the Times said.

"We are aware of the article and are reviewing its contents with our technical experts," WHO spokesman Tarik Jasarevic said in an email reply on Monday to a Reuters request for comment.

The extent to which the coronavirus can be spread by the so-called airborne or aerosol route - as opposed to by larger droplets in coughs and sneezes - remains disputed.

Any change in the WHO's assessment of the risk of transmission could affect its current advice on keeping one-metre physical distancing. Governments, which also rely on the agency for guidance policy, may also have to adjust public health measures aimed at curbing the spread of the virus.

"Especially in the last couple of months, we have been stating several times that we consider airborne transmission as possible but certainly not supported by solid or even clear evidence," Benedetta Allegranzi, the WHO's technical lead for infection prevention and control, was quoted as saying in the New York Times.

WHO guidance to health workers, dated June 29, says that SARS-CoV-2, the virus that causes Covid-19, is primarily transmitted between people through respiratory droplets and on surfaces.

But airborne transmission via smaller particles is possible in some circumstances, such as when performing intubation and aerosol-generating procedures, it says.

Medical workers performing such procedures should wear heavy-duty N95 respiratory masks and other protective equipment in an adequately ventilated room, the WHO says.

Officials at South Korea's Centers for Disease Control said on Monday they were continuing to discuss various issues about Covid-19, including the possible airborne transmission. They said more investigations and evidence were needed.

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Agencies
August 2,2020

Washington, Aug 2: Children under the age of five have between 10 to 100 times greater levels of genetic material of the coronavirus in their noses compared to older children and adults, a study in JAMA Pediatrics said Thursday.

Its authors wrote this meant that young children might be important drivers of Covid-19 transmission within communities -- a suggestion at odds with the current prevailing narrative.

The paper comes as the administration of US President Donald Trump is pushing hard for schools and daycare to reopen in order to kickstart the economy.

Between March 23 and April 27, researchers carried out nasal swab tests on 145 Chicago patients with mild to moderate illness within one week of symptom onset.

The patients were divided into three groups: 46 children younger than five-years-old, 51 children aged five to 17 years, and 48 adults aged 18 to 65 years.

The team, led by Dr Taylor Heald-Sargent of the Ann & Robert H. Lurie Children's Hospital, observed, "a 10-fold to 100-fold greater amount of SARS-CoV-2 in the upper respiratory tract of young children."

15 countries with the highest number of cases, deaths due to the Covid-19 pandemic

The authors added that a recent lab study had demonstrated that the more viral genetic material was present, the more infectious virus could be grown.

It has also previously been shown that children with high viral loads of the respiratory syncytial virus (RSV) are more likely to spread the disease.

"Thus, young children can potentially be important drivers of SARS-CoV-2 spread in the general population," the authors wrote.

"Behavioral habits of young children and close quarters in school and daycare settings raise concern for SARS-CoV-2 amplification in this population as public health restrictions are eased," they concluded.

The new findings are at odds with the current view among health authorities that young children -- who, it has been well established, are far less likely to fall seriously ill from the virus -- don't spread it much to others either.

However, there has been fairly little research on the topic so far.

One recent study in South Korea found children aged 10 to 19 transmitted Covid-19 within households as much as adults, but children under nine transmitted the virus at lower rates.

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