Court hill loses its green cover forever

Washington D.C., May 8: The prime time for brain development in a child's life is the first year, where the infant spends most of the time asleep. It is the time when neural connections form and sensory memories are encoded.

However, when sleep is disrupted, as occurs more often among children with autism, brain development may be affected, too.

New research led by the University of Washington finds that sleep problems in a baby's first 12 months may not only precede an autism diagnosis but also may be associated with altered growth trajectory in a key part of the brain, the hippocampus.

The study, which was published in the American Journal of Psychiatry, researchers report that in a sample of more than 400 taken of 6- to 12-month-old infants, those who were later diagnosed with autism were more likely to have had difficulty falling asleep.

It also states that this sleep difficulty was associated with altered growth trajectories in the hippocampus.

"The hippocampus is critical for learning and memory, and changes in the size of the hippocampus have been associated with poor sleep in adults and older children.

As many as 80 per cent of the children with autism spectrum disorder have sleep problems," said Annette Estes, director of the UW Autism Center and senior author of the study.

"In our clinical experience, parents have a lot of concerns about their children's sleep, and in our work on early autism intervention, we observed that sleep problems were holding children and families back," added Estes, who is also a UW professor of speech and hearing sciences.

"It could be that altered sleep is part-and-parcel of autism for some children. One clue is that behavioural interventions to improve sleep don't work for all children with autism, even when their parents are doing everything just right. This suggests that there may be a biological component to sleep problems for some children with autism," said Estes.

To consider links among sleep, brain development, and autism, researchers at the IBIS Network looked at MRI scans of 432 infants, surveyed parents about sleep patterns, and measured cognitive functioning using a standardized assessment.

At the outset of the study, infants were classified according to their risk for developing autism: Those who were at higher risk of developing autism -- about two-thirds of the study sample -- had an older sibling who had already been diagnosed.

Infant siblings of children with autism have a 20 per cent chance of developing autism spectrum disorder -- a much higher risk than children in the general population.

In the current study, 127 of the 432 infants were identified as "low risk" at the time the MRI scans were taken because they had no family history of autism.

They later evaluated all the participants at 24 months of age to determine whether they had developed autism. Of the roughly 300 children originally considered "high familial risk," 71 were diagnosed with autism spectrum disorder at that age.

Problems with sleep were more common among the infants later diagnosed with an autism spectrum disorder, as were larger hippocampi. No other subcortical brain structures were affected, including the amygdala, which is responsible for certain emotions and aspects of memory, or the thalamus, a signal transmitter from the spinal cord to the cerebral cortex.

The authors note that while parents reported more sleep difficulties among infants who developed autism compared to those who did not, the differences were very subtle and only observed when looking at group averages across hundreds of infants.

Sleep patterns in the first years of life change rapidly as infants transition from sleeping around the clock to a more adult-like sleep/wake cycle. Until further research is completed, Estes said, it is not possible to interpret challenges with sleep as an early sign of increased risk for autism.

Mangaluru, May 9: A team of doctors at Mangaluru's Mangala Hospital has developed a 'bubble helmet' that will provide an alternative to patients who need an oxygen mask.

The team was led by Dr Ganapathi, medical director of Mangala Hospital and Mangala Kidney Foundation in the city.

The bubble helmet, which has a special collar attached to it, helps the patients with breathing issues, and to avoid using ventilator facility.

Dr Ganapathi said, "When a patient needs intubation we will be providing them oxygen bubble helmets and we will first give it a trial before we intubate a patient."

"I have converted an ordinary snorkelling mask into a ventilator assist device, this mask can be used as a personal protection device by connecting it to a bacterial viral filter," he added.

Dr Ganapathi said that the connector has been made available in India and a snorkelling mask can be easily converted into a ventilator assist device. And it will make the management of coronavirus patients easy.

Bengaluru, Jul 2: As many as 3,363 students from Covid-19 containment zones have appeared for SSLC examinations in different parts of Karnataka till yesterday. On the first day of exam, i.e., on June 25, only 998 students these zones had written the exam.

In the past few days the number of containment zones has increased across the state in general and Bengaluru in particular. In all, 32 students could not appear for the exam as they turned positive.

While on June 25, the number of students who were found unwell during the check up at exam centre was 201, it was 613 on Wednesday. Students who are sick and those from the containment zones take the exam in a different room.

The social science exam on Wednesday saw an attendance percentage of 97.96 (7.68 lakh). This was against 98.78% last year. There were 7.45 lakh fresh candidates, 20,000 private candidates and 593 from outside the state.

Five students in Yadgir district were given question papers based on the old syllabus for maths exam on June 27. Their answerscripts will be evaluated separately and action will be taken against the officials.

Malpractices assisted by schools by switching off CCTV cameras were reported in Ballari and Koppal. “We’ve completed all the core subjects. Now only languages are left. We’ll complete them too in a safe environment,” said S Suresh Kumar, primary and secondary education minister.