Night workers find diabetes harder to control: study

April 4, 2017

Bangkok, Apr 4: People with type 2 diabetes have poorer control over their blood glucose levels when they work the night shift compared with those who work in the daytime or are unemployed, a new study has found.

nightshiftThe study shows that poor long-term glycemic, or blood sugar, control, was independent of what workers ate or any sleep problems they had.

The findings expand on previous research showing that night shift work is associated with an increased risk for the development of diabetes.

"Previously, there were little data whether people who already have type 2 diabetes and work the night shift have trouble controlling their blood sugars," said Sirimon Reutrakul, associate professor at Mahidol University in Thailand.

"Our study data raise awareness of the difficulty in diabetes control among night shift workers," said Reutrakul.

Reutrakul and her colleagues studied 260 individuals with type 2 diabetes in Thailand: 62 night shift workers, 94 daytime workers and 104 unemployed individuals.

They determined the study participants' glycemic control by reviewing their medical records for recent measurements of hemoglobin A1C.

The A1C test shows the average blood sugar level over the previous three months. Most people with diabetes should strive for an A1C level below 7 per cent, according to the Hormone Health Network.

Night shift workers reportedly had an average A1C of 8.2 per cent, significantly higher than the 7.6 per cent A1C for daytime workers and 7.5 per cent A1C for participants who did not work.

On questionnaires, night shift workers also reported shorter sleep duration, higher daily intake of calories and higher body mass index, or BMI (an estimate of body fat), than did the other two groups.

Even after the researchers adjusted their statistical analyses for factors that could affect glucose metabolism, including sleep duration, dietary intake and BMI, the significant association between shift work and glycemic control remained, Reutrakul said.

"Diabetic individuals who work at night should pay special attention to managing their disease through healthy eating, regular exercise and optimal use of medications prescribed by their physician," Reutrakul added.

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Agencies
April 14,2020

There is no evidence that the Bacille Calmette-Guerin (BCG) vaccine, which is primarily used against tuberculosis, protects people against infection with the novel coronavirus, the World Health Organization (WHO) said.

The WHO therefore didn't recommend BCG vaccination for the prevention of COVID-19 in the absence of evidence, according to its daily situation report on Monday, Xinhua news agency reported.

"There is experimental evidence from both animal and human studies that the BCG vaccine has non-specific effects on the immune system. These effects have not been well characterized and their clinical relevance remains unknown," WHO stated.

Two clinical trials addressing the question are underway, and WHO will evaluate the evidence when it is available, it noted.

BCG vaccination prevents severe forms of tuberculosis in children and diversion of local supplies may result in an increase of disease and deaths from the tuberculosis, it warned.

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Agencies
January 4,2020

Washington D.C., Jan 3: A new study has found out that diet significantly affects the mental health and well being of an individual.

The study was published in the journal European Neuropsychopharmacology.

"We have found that there is increasing evidence of a link between a poor diet and the worsening of mood disorders, including anxiety and depression. However, many common beliefs about the health effects of certain foods are not supported by solid evidence," said the lead researcher, Professor Suzanne Dickson.

According to the researchers, the link between diet and mental health can be firmly established in certain cases like that of the ability of a ketogenic diet being helpful for children with epilepsy and the impact of vitamin B12 deficiency on poor memory, depression and fatigue.

"With individual conditions, we often found very mixed evidence. With ADHD for example, we can see an increase in the quantity of refined sugar in the diet seems to increase ADHD and hyperactivity, whereas eating more fresh fruit and vegetables seems to protect against these conditions," said Dickson

But there are comparatively few studies, and many of them don't last long enough to show long-term effects," added Dickson.

The study further concludes that some food items can be associated with treatment and the betterment of certain mental health conditions.

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Agencies
April 17,2020

Washington DC, Apr 17: In recent research, scientists have linked the emotional, social and psychiatric problems in children and adolescents with higher levels of genetic vulnerability for adult depression. The study implies that the genetics passed from parents may be linked with psychiatric problems in children and adolescents and may also leading to depression in adults.

University of Queensland scientists made the finding while analysing the genetic data of more than 42,000 children and adolescents from seven cohorts across Finland, the Netherlands, Norway, Sweden and the UK.

Professor Christel Middeldorp said that researchers have also found a link with a higher genetic vulnerability for insomnia, neuroticism and body mass index.

"By contrast, study participants with higher genetic scores for educational attainment and emotional well-being were found to have reduced childhood problems," Professor Middeldorp said.

"We calculated a person's level of genetic vulnerability by adding up the number of risk genes they had for a specific disorder or trait and then made adjustments based on the level of importance of each gene We found the relationship was mostly similar across ages," Middeldorp added.

The results indicate there are shared genetic factors that affect a range of psychiatric and related traits across a person's lifespan.

Middeldorp said that around 50 per cent of children and adolescents with psychiatric problems, such as attention deficit hyperactivity disorder (ADHD), continue to experience mental disorders as adults, and are at risk of disengaging with their school community among other social and emotional problems.

"Our findings are important as they suggest this continuity between childhood and adult traits is partly explained by genetic risk," the Professor said.

"Individuals at risk of being affected should be the focus of attention and targeted treatment," Middeldorp continued.

"Although the genetic vulnerability is not accurate enough at this stage to make individual predictions about how a person's symptoms will develop over time, it may become so in the future, in combination with other risk factors. And, this may support precision medicine by providing targeted treatments to children at the highest risk of persistent emotional and social problems," Middeldorp added.

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