Now, barcode scanner microscope for better disease imaging

February 23, 2017

Melbourne, Feb 23: Australian engineers have developed an advanced microscope using barcode laser scanner technology that may help doctors better analyse complex medical conditions ranging from blood disorders and cancer to neurological disorders.

The microscope can film moving blood cells and neurons firing in living animals and is much more powerful than similar microscopes available commercially.

barcode1"Scientists can use our new microscope to analyse complex medical problems ranging from blood disorders and cancer to neurological disorders," said lead researcher, Steve Lee from Australian National University (ANU).

"The microscope can speed up or slow down to capture the slow moving cells in a blood stream or live neurons firing rapidly in the brain, making it much more flexible than other microscopes on the market," said Lee.

Lee said the microscope used technology similar to retail barcode scanners and office laser printers.

In barcode scanners, a laser beam bounces off a spinning polygon mirror, allowing it to scan across a sample very quickly.

A barcode scanner registers a sequence of patterns to identify a product. A polygon mirror usually has around 10 mirror facets.

Lee said the team's microscope used a more powerful laser beam as the light source and up to 36 mirror facets to scan the laser beam across the biological sample in a few thousandths of a second.

"We achieve the same imaging resolution of conventional scanning microscopes on the market but at double the speed," he said.

"The innovation here is that we modernised the polygon mirror microscopy system with advanced electronics and software controls to enable real-time imaging applications, with up to 800 frames per second," Lee added.

Yongxiao Li, a PhD student from the ANU Research School of Engineering, said the customised open-source software made the microscope a flexible imaging tool.

The research was published in the Journal of Biophotonics.

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Agencies
July 19,2020

New Delhi, Jul 19: Indian equities will be driven by a host of factors like corporate earnings, coronavirus cases trend and geo-political developments this week, according to analysts.

Market participants will also keenly watch the progress of monsoon, with experts saying that the farm sector revival will play a key role in lifting the coronavirus-hit economy.

"With no major event, the ongoing earnings season and global cues will continue to dictate the market trend. Besides, the progress of monsoon will also be closely watched," Ajit Mishra, VP - Research, Religare Broking, said.

Globally, the rising coronavirus infections and geo-political tensions have created uncertainty on the economic recovery front.

With India's COVID-19 cases fast approaching the 11 lakh mark, the third-highest behind the US and Brazil, and the death toll nearing 27,000, participants are expected to tread cautiously going forward.

At global level, confirmed COVID-19 cases have crossed 1.4 crore and deaths totalled about 6 lakh.

Markets globally will closely follow developments on the trade and political level between the US and China, according to analysts.

"We would continue witnessing stock-specific action as the earnings season unfold. Though the near-term momentum looks positive, we would advise traders to be cautious, given flaring US-China trade relations, persistent rise in virus cases and implementation of fresh lockdowns in parts of the country," said Siddhartha Khemka, Head - Retail Research, Motilal Oswal Financial Services Ltd.

HDFC Bank will remain in focus on Monday after having announced its June quarter earnings on Saturday.

The lender reported 19.6 per cent rise in its standalone net profit at Rs 6,658.62 crore for April-June 2020; while its income rose to Rs 34,453.28 crore during the quarter.

Other major companies to announce their quarterly results this week are Axis Bank, Bajaj Finance, Hindustan Unilever Limited, Bajaj Auto and ITC.

"Going ahead market participants will closely track the development related to covid vaccine, the rising infection of coronavirus, development on economic activities, corporate earnings and US-China relationship," said Sumeet Bagadia, Executive Director, Choice Broking.

On weekly basis, the Sensex gathered 425.81 points or 1.16 per cent, and the Nifty gained 133.65 points or 1.24 per cent.

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Agencies
August 2,2020

New Delhi, Aug 2: The National Commission for Women (NCW) has issued notice to some Bollywood celebrities named in a complaint against the promoter of a company for allegedly blackmailing and sexually assaulting a number of girls on the pretext of giving them a career in modelling.

Taking cognizance of the complaint filed by social activist Yogita Bhayana of People Against Rape in India (PARI), the NCW scheduled a virtual hearing presided by its chairperson on August 6.

The complaint against Sunny Verma, promoter of a company named IMG Ventures with its headquarter in Chandigarh, alleged that he has been blackmailing and sexually assaulting a number of girls on the pretext of giving them career in modelling.

PARI's Yogita Bhayana wrote a complaint letter to NCW chairperson Rekha Sharma.

"Through his company, he (Sunny Verma) invites the girls on the pretext of organising a Miss Asia contest with a claim that the contest will launch them as models. To make it look genuine, his company has also been taking an entry fee of Rs 2,950. Once the girls apply, they are alluded by the female accomplices of Sunny Verma to submit their nude pictures in order to get the better ranking in the contest," the complaint letter said on July 31.

It alleged that Verma, after receiving the pictures and sometimes even before, used to get in touch with the girls and ask for completely nude pictures and videos.

The complaint letter said that Verma also used to allude as well as threaten the girls to submit to his sexual desires if they were interested in modelling as a career or wish to win the contest.

"Once he established a physical relationship with the girls, he used to blackmail them for regular sexual favours. Many girls from across the country have suffered a sexual and mental assault from Sunny and his accomplices," said the complaint citing several letters, texts and audio clips from several girls as proof of this modus operandi of Sunny Verma and his company.

The complaint also said that Sunny Verma has been previously also arrested on charges of sexual assault.

"We would demand that NCW should investigate the case to its depth and get the guilty punished so that any other person should not dare to exploit these kinds of innocent girls on any pretext. It will be a message to people like Sunny Verma and all associated Bollywood stars. Looking forward to strict action from NCW against sexual offenders like Sunny Verma & others," the complaint said.

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Agencies
June 19,2020

Denser places, assumed by many to be more conducive to the spread of the coronavirus that causes COVID-19, are not linked to higher infection rates, say researchers.

The study, led by Johns Hopkins University, published in the Journal of the American Planning Association, also found that dense areas were associated with lower COVID-19 death rates.

"These findings suggest that urban planners should continue to practice and advocate for compact places rather than sprawling ones, due to the myriad well-established benefits of the former, including health benefits," says study lead author Shima Hamidi from Johns Hopkins Bloomberg School of Public Health in the US.

For their analysis, the researchers examined SARS-CoV-2 infection rates and COVID-19 death rates in 913 metropolitan counties in the US.

When other factors such as race and education were taken into account, the authors found that county density was not significantly associated with county infection rate.

The findings also showed that denser counties, as compared to more sprawling ones, tended to have lower death rates--possibly because they enjoyed a higher level of development including better health care systems.

On the other hand, the research found that higher coronavirus infection and COVID-19 mortality rates in counties are more related to the larger context of metropolitan size in which counties are located.

Large metropolitan areas with a higher number of counties tightly linked together through economic, social, and commuting relationships are the most vulnerable to the pandemic outbreaks.

According to the researchers, recent polls suggest that many US citizens now consider an exodus from big cities likely, possibly due to the belief that more density equals more infection risk.

Some government officials have posited that urban density is linked to the transmissibility of the virus.

"The fact that density is unrelated to confirmed virus infection rates and inversely related to confirmed COVID-19 death rates is important, unexpected, and profound," said Hamidi.

"It counters a narrative that, absent data and analysis, would challenge the foundation of modern cities and could lead to a population shift from urban centres to suburban and exurban areas," Hamidi added.

The analysis found that after controlling for factors such as metropolitan size, education, race, and age, doubling the activity density was associated with an 11.3 per cent lower death rate.

The authors said that this is possibly due to faster and more widespread adoption of social distancing practices and better quality of health care in areas of denser population.

The researchers concluded that a higher county population, a higher proportion of people age 60 and up, a lower proportion of college-educated people, and a higher proportion of African Americans were all associated with a greater infection rate and mortality rate.

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