Now, climate-based system could predict dengue spread in India

Agencies
September 3, 2017

London, Sept 3: Scientists have developed a system that can predict the spread of dengue in different parts of India, based on climatic factors, an advance that may help take preventive measures against the deadly infection.

Researchers from the University of Liverpool in the UK identified the climatic risks for dengue disease outbreaks in different climatic zones in the country through the states of Punjab, Haryana, Rajasthan, Gujarat and Kerala. The team, in collaboration with researchers from Indian Institute of Chemical Technology (IICT) in Hyderabad and National Institute of Pharmaceutical Education and Research

(NIPER) in Guwahati, focused on changes in a factor called 'extrinsic incubation period (EIP)' of the dengue virus by taking into account daily and monthly mean temperatures in these areas.

EIP is the time taken for incubation of the virus in the mosquito. During this period, after the mosquito draws a virus-rich-blood meal, the virus escapes the gut, passes through the mosquito's body and reaches it salivary glands. Once this happens, the mosquito is infectious and capable of transmitting the virus to a human host. It has been found that climatic conditions play an important role in EIP.

Lower temperatures (17-18 degrees Celsius) result in longer EIPs thereby leading to decreased virus transmission. With increasing temperatures, feeding increases because of enhanced metabolism of the mosquito, leading to shorter EIPs. Even a five-day decrease in the incubation period can hike transmission rate by three times, and with an increase in temperature from 17 to 30 degrees Celsius, dengue transmission increases fourfold.

However, a further increase in temperature beyond 35 degrees Celsius is detrimental to the mosquito survival. Researchers observed that except for Gujarat which comprises of arid regions, there was a strong correlation between rainfall and dengue disease burden.

They propose an increase in breeding grounds for mosquitoes as a major reason for this finding. The study found that Kerala being warm (temperature range 23.5-30 degrees Celsius) and wet and with short EIPs (9-14 days) experiences the highest number of dengue cases.

It has been found that EIP is the shortest during the monsoon season in most states and therefore there is an enhanced risk of dengue during this time. It is important to take into account the dynamic EIP estimates in different regions in assessing disease burden. "This climate-based dengue forecasting model could help health authorities to assess the disease intensity in a geographic region, based on that they can plan disease control operations well in advance and optimise the use of resources meticulously," said Srinivasa Rao Mutheneni of IICT, who led the study.

Changes in temperature affecting the extrinsic incubation period of the virus, future changes in the climate might have a substantial effect on dengue and other vector-borne disease burden in India.

"Though such methods are in vogue for disease control operations, we are still in the initial stages of implementation of such strategic control methods," Rao said. "Factors such as population density and migration also need to be included for future risk assessment studies," he said.

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Agencies
March 11,2020

With the sales of chicken and mutton going down due to the coronavirus scare, it is the humble 'Kathal' (jackfruit) is emerging as an acceptable alternative.

'Kathal' is now selling at ₹120 per kilogram -- an increase of more than 120 per cent over the normal ₹50 per kilogram.

The jackfruit, in fact, is now priced higher than chicken which is selling at ₹80 per kilogram due to poor demand.

"It is better having a 'Kathal' biryani instead of a mutton biryani. It tastes reasonably good. The only problem is that 'Kathal' has been sold out in the vegetable market and is difficult to find," said Purnima Srivastava whose family savours non-vegetarian food on a regular basis.

The corona scare has hit poultry business so hard and the Poultry Farm Association recently organized a Chicken Mela in Gorakhpur to dispel the misconception that birds are carriers of the deadly virus.

"In fact, we gave away plateful of chicken dishes for Rs 30 to encourage people to savour the delicacies. We cooked one thousand kilograms of chicken for the Mela and the entire stock was sold out," said Vineet Singh, head of the Poultry Farm Association.

However, the Mela did not do much to dispel the fears about chicken, mutton or fish consumption amid the virus outbreak.

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Agencies
May 17,2020

Geneva, May 17: Spraying disinfectant on the streets, as practised in some countries, does not eliminate the new coronavirus and even poses a health risk, the World Health Organization (WHO) warned on Saturday.

In a document on cleaning and disinfecting surfaces as part of the response to the virus, the WHO says spraying can be ineffective. "Spraying or fumigation of outdoor spaces, such as streets or marketplaces, is... not recommended to kill the Covid-19 virus or other pathogens because disinfectant is inactivated by dirt and debris," explains the WHO.

"Even in the absence of organic matter, chemical spraying is unlikely to adequately cover all surfaces for the duration of the required contact time needed to inactivate pathogens." The WHO said that streets and pavements are not considered as "reservoirs of infection" of Covid-19, adding that spraying disinfectants, even outside, can be "dangerous for human health".

The document also stresses that spraying individuals with disinfectants is "not recommended under any circumstances".

"This could be physically and psychologically harmful and would not reduce an infected person's ability to spread the virus through droplets or contact," said the document.

Spraying chlorine or other toxic chemicals on people can cause eye and skin irritation, bronchospasm and gastrointestinal effects, it adds.

The organisation is also warning against the systematic spraying and fumigating of disinfectants on to surfaces in indoor spaces, citing a study that has shown it to be ineffective outside direct spraying areas.

"If disinfectants are to be applied, this should be done with a cloth or wipe that has been soaked in disinfectant," it says.

The SARS-CoV-2 virus, the cause of the pandemic that has killed more than 300,000 people worldwide since its appearance in late December in China, can attach itself to surfaces and objects.

However, no precise information is currently available for the period during which the viruses remain infectious on the various surfaces.

Studies have shown that the virus can stay on several types of surfaces for several days. However, these maximum durations are only theoretical because they are recorded under laboratory conditions and should be "interpreted with caution" in the real-world environment.

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Agencies
March 27,2020

New Delhi, Mar 27: The Centre has restricted sale and distribution of "hydroxychloroquine" declaring it as an essential drug to treat the COVID-19 patients and meet the requirements of emergency arising due to the pandemic.

The Ministry of Health and Family Welfare on Thursday made the announcement making it clear that the order "shall come into force on the date of its publication in the official Gazette".

In the order, the government declared that the Central government is "satisfied that the drug hydroxychloroquine is essential to meet the requirements of emergency arising due to pandemic COVID-19 and in the public interest, it is necessary and expedient to regulate and restrict the sale and distribution of the drug 'hydroxychloroquine' and preparation based thereon for preventing their misuse".

"Now, therefore, in exercise of the powers conferred by Section 26B of the Drugs and Cosmetics Act, 1940 (23 of 1940), the Central government hereby directs that sale by retail of any preparation containing the drug Hydroxychloroquine shall be in accordance with the conditions for sale of drugs specified in Schedule H1 to the Drugs and Cosmetics Rules, 1945."

The order came at a time when the novel coronavirus claimed 16 lives and infected over 600 people across India.

The announcement regarding ban of sale and distribution of the drug was made by the government earlier but it issued an official Gazette notification on Thursday signalling that hydroxychloroquine -- an anti-Malaria drug -- will work as a medicine for treating coronavirus infected patients as well.

Recently, the national task force for COVID-19 constituted by Indian Council for Medical Research (ICMR) has recommended hydroxy-chloroquine as a preventive medication.

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