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New Delhi, May 6: The death toll due to COVID-19 rose to 1,694 and the number of cases climbed to 49,391 in the country on Wednesday, registering an increase of 126 deaths and 2,958 cases in the last 24 hours, the Union Health Ministry said.

The number of active COVID-19 cases is 33,514. A total of 13,160 people have recovered and one patient has migrated, it said.

"Thus, around 28.71 per cent patients have recovered so far," a senior health ministry official said.

The total number of cases include 111 foreign nationals.

A total of 111 deaths were reported since Tuesday evening, of which 49 fatalities were reported from Gujarat, 34 from Maharashtra, 12 from Rajasthan, seven from West Bengal, three from Uttar Pradesh, two each from Punjab and Tamil Nadu and one each from Karnataka and Himachal Pradesh, the ministry said.

Of the 1,694 fatalities, Maharashtra tops the tally with 617 fatalities. Gujarat comes second with 368 deaths, followed by Madhya Pradesh at 176, West Bengal at 140, Rajasthan at 89, Delhi at 64, Uttar Pradesh at 56 and Andhra Pradesh at 36.

The death toll reached 33 in Tamil Nadu, 29 in Telengana, while Karnataka has reported 29 fatalities.

Punjab has registered 25 COVID-19 deaths, Jammu and Kashmir eight, Haryana six and Kerala and Bihar four deaths each.

Jharkhand has recorded three COVID-19 fatalities.

Meghalaya, Chandigarh, Himachal Pradesh, Odisha, Assam and Uttarakhand have reported one fatality each, according to the ministry data.

According to the health ministry data updated in the morning, the highest number of confirmed cases in the country are from Maharashtra at 15, 525, followed by Gujarat at 6,245, Delhi at 5,104, Tamil Nadu at 4,058, Rajasthan at 3,158, Madhya Pradesh at 3,049 and Uttar Pradesh at 2,880.

The number of COVID-19 cases has gone up to 1,717 in Andhra Pradesh and 1,451 in Punjab.

It has risen to 1,344 in West Bengal, 1,096 in Telengana, 741 in Jammu and Kashmir, 671 in Karnataka, 548 in Haryana and 536 in Bihar.

Kerala has reported 502 coronavirus cases so far, while Odisha has 175 cases. A total of 125 people have been infected with the virus in Jharkhand and 111 in Chandigarh.

Uttarakhand has reported 61 cases, Chhattisgarh 59 cases, Assam 43, Himachal Pradesh 42 and Ladakh 41.

Thirty-three COVID-19 cases have been reported from the Andaman and Nicobar Islands.

Tripura has registered 43 cases, Meghalaya has reported 12 and Puducherry nine, while Goa has seven COVID-19 cases.

Manipur has two cases. Mizoram, Arunachal Pradesh and Dadar and Nagar Haveli have reported a case each.

"Our figures are being reconciled with the ICMR," the ministry said on its website.

State-wise distribution is subject to further verification and reconciliation, it said.

New Delhi, May 26: As India ranked 10th in the global infection list, overtaking Iran, which was an early hotspot of coronavirus, India's top medical body has said the human trials of COVID-19 vaccine may begin at least in six months.

Dr. Rajni Kant, Director Regional Medical Research Centre and Head at the Indian Council of Medical Research (ICMR) said, "The virus strain isolated at the National Institute of Virology (NIV) laboratory in Pune will be used to develop the vaccine, and this strain has been successfully transferred to the Bharat Biotech International Ltd. (BBIL). It is expected that the human trials of the vaccine will begin in at least six months."

Queried on the focus areas as India inches closer to 1.4 lakh COVID-19 cases, Kant said we should not get anxious about the rapid increase in numbers, especially in the past week, which saw 5,000 Covid-19 cases daily, instead focus on protecting the most vulnerable group.

"We should not fear from increasing Covid-19 cases. The elderly and people with comorbidities need protection. This is the highly vulnerable group, and we need to deploy resources and develop strategies to keep the mortality rate as low as possible in this group," said Kant.

Initially, it was assumed that the country would require thousands of ventilators, but last week, the health ministry said only 0.45 per cent of COVID-19 cases need ventilator support.

Kant insisted the focus should be on five per cent to 10 per cent serious patients. "We are testing more than one lakh daily and our case fatality rate is already one of the lowest in the world. In absence of vaccine, people should follow social distancing guidelines," he added

On the significance of the recovery rate, Kant said the increasing recovery rate of the COVID-19 patients, which is at 41 per cent, is a bright spot in India's fight against deadly viral infection.

Queried on large scale COVID-19 cases in Mumbai, Delhi and Ahmedabad, Kant said the population density in these regions is very high, which proves to be the just right environment for the viral infection.

He insisted on developing robust cluster management strategies in the hard-hit coronavirus spots, and the movement of people should be curtailed in these areas.

"Currently, a lot of people are moving around easily and avoiding social distancing norms. The first phase of the lockdown was very effective, but now things have changed," added Kant.