Over 5,000 volunteers in Wuhan sign up for clinical trials over Covid19 vaccine

News Network
March 25, 2020

Beijing, Mar 25: Around 5,000 people have signed up for the phase I clinical trial of recombinant novel coronavirus vaccine in Chinese city Wuhan where the virus first emerged late last year.

The recruitment for participants ended this week with nearly 5,000 volunteers signing up for the trial, state-run Beijing News reported on Wednesday.

A single-centre, open and dose-escalation phase I clinical trial for recombinant novel coronavirus vaccine (adenoviral vector) will be tested in healthy adults aged between 18 and 60 years, according to the ChiCTR (China Clinical Trial Register).

The trial, led by experts from the Academy of Military Medical Sciences, gained its approval on March 16 and the research is expected to last half a year.

Requiring at least 108 participants, the trial will be conducted in Wuhan, capital of Hubei province, the region worst-affected by the virus in the country, state-run China Daily reported.

Participants will experience 14-day quarantine restrictions after being vaccinated and their health condition will be recorded every day.

Chinese scientists are hastening the development of COVID-19 vaccines through five approaches --- inactivated vaccines, genetic engineering subunit vaccines, adenovirus vector vaccines, nucleic acid vaccines and vaccines using attenuated influenza virus as vectors.

So far, most teams are expected to complete preclinical research in April and some are moving forward faster, Wang Junzhi, an academician with the Chinese Academy of Engineering said.

Wang noted that research and development of COVID-19 vaccines in China is not slower than foreign counterparts and has been carried out in a scientific, standardised and orderly way.

China has stepped up the process to finalise vaccines to counter COVID-19 after Kaiser Permanente research facility in Seattle and Washington stole the march and began human trials.

China lifted tough restrictions on the Hubei province on Wednesday after a months-long lockdown as the country reported no new domestic cases.

But there were another 47 imported infections from overseas, the National Health Commission said. In total, 474 imported infections have been diagnosed in China -- mostly Chinese nationals returning home.

Comments

Y UDAYA CHANDAR
 - 
Monday, 13 Apr 2020

Dear Sir,

 

I am 77 but a very healthy person with remarkable immunity. I contracted Malaria fever in 1994 because of mosquito biting and I have not been sick anytime there after, not even for ordinary fever in the last 26 years.

 

I am sure you would like to conduct the trials on persons of varying criteria. I am sure you don't want to carry out the trials on perfectly healthy young individuals only. 

 

I am certain that  you want to try the vaccine on a 'common man' from 'general public.' I am ready for the trial and you can take me. I will be delighted. 

 

If you are not handling this matter kindly forward this mail to the correct agency.

 

I look forward to hearing from you.

 

Best regards.

 

If you are not moving forward, you are really moving backward.

Y Udaya Chandar

 

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News Network
April 17,2020

The coronavirus pandemic has sickened more than 2,425,000 people, according to official counts. So far at least 164,000 people have died, and the virus has been detected in at least 177 countries, as the following table shows.

United States 

780,330

37,782

Spain

200,210

20,852

Italy 

181,228

24,114

Germany

141,672

4,404

U.K.

124,743

16,509

France

114,657

20,265

Turkey

90,980

2,140

Mainland China

88,466

4,632

Iran

83,505

5,209

Russia

47,121

405

Brazil

40,743

2,587

Belgium

39,983

5,828

Canada

36,823

1,690

Netherlands

33,405

3,751

Switzerland

27,944

1,142

Portugal

20,863

735

India

18,539

592

Peru

16,325

445

Ireland

15,652

687

Austria

14,795

470

Sweden

14,777

1,580

Israel

13,713

177

Japan

10,915

168

South Korea

10,674

236

Chile

10,507

139

Saudi Arabia

10,484

103

Ecuador

10,128

507

Poland

9,593

380

Romania

8,936

478

Mexico

8,772

712

Pakistan

8,418

176

Singapore

8,014

11

Denmark

7,515

364

U.A.E.

7,265

43

Norway

7,156

181

Czech Republic

6,900

194

Indonesia

6,760

590

Serbia

6,630

125

Australia

6,625

71

Philippines

6,459

428

Belarus

6,264

51

Qatar

6,015

9

Ukraine

5,710

151

Malaysia

5,425

89

Dominican Rep.

4,964

235

Panama

4,467

126

Colombia

3,977

189

Finland

3,868

98

Luxembourg

3,558

75

Egypt

3,333

250

South Africa

3,300

58

Morocco

3,046

143

Bangladesh

2,948

101

Argentina

2,941

136

Thailand

2,792

47

Algeria

2,718

384

Moldova

2,548

70

Greece

2,245

116

Kuwait

1,995

9

Hungary

1,984

199

Bahrain

1,907

7

Croatia

1,881

47

Kazakhstan

1,852

19

Iceland

1,773

10

Uzbekistan

1,627

5

Iraq

1,574

82

Estonia

1,535

40

New Zealand

1,440

12

Azerbaijan

1,436

19

Oman

1,410

7

Armenia

1,339

22

Slovenia

1,335

77

Lithuania

1,326

37

Bosnia and Herzegovina

1,309

49

North Macedonia

1,225

54

Slovakia

1,173

13

Cameroon

1,163

42

Cuba

1,087

36

Ghana

1,042

9

Afghanistan

1,026

36

Hong Kong

1,025

4

Bulgaria

929

43

Tunisia

884

38

Ivory Coast

847

9

Djibouti

846

2

Cyprus

772

12

Latvia

739

5

Andorra

717

37

Lebanon

677

21

Nigeria

665

22

Costa Rica

662

6

Niger

648

20

Guinea

622

5

Albania

584

26

Burkina Faso

581

38

Kyrgyzstan

568

7

Bolivia

564

33

Uruguay

535

10

Kosovo

510

12

Channel Islands

488

24

Honduras

477

46

San Marino

462

39

West Bank & Gaza

449

3

Malta

431

3

Jordan

425

7

Taiwan

422

6

Georgia

402

4

Senegal

377

5

Congo

332

25

Mauritius

328

9

Montenegro

312

5

Sri Lanka

304

7

Isle of Man

300

9

Guatemala

289

7

Kenya

281

14

Vietnam

268

Venezuela

256

9

Tanzania

254

10

Mali

246

14

Somalia

237

8

Jamaica

223

5

El Salvador

218

7

Paraguay

208

8

Faroe Islands

185

Republic of the Congo

160

6

Rwanda

147

Brunei

138

1

Gibraltar

132

Cambodia

122

Madagascar

121

Gabon

120

1

Myanmar

119

5

Trinidad and Tobago

114

8

Ethiopia

111

3

Sudan

107

12

Liberia

99

8

Aruba

97

2

Monaco

94

3

Bermuda

86

5

Togo

84

6

Liechtenstein

81

1

Equatorial Guinea

79

Barbados

75

5

Maldives

69

Cape Verde

67

1

Sint Maarten

67

10

Cayman Islands

66

1

Guyana

65

7

Zambia

65

3

Bahamas

60

9

Haiti

57

3

Uganda

56

Benin

54

1

Libya

51

1

Guinea-Bissau

50

Macau

45

Sierra Leone

43

Eritrea

39

Mozambique

39

Syria

39

3

Chad

33

Mongolia

33

Nepal

31

Zimbabwe

25

3

Angola

24

2

Eswatini

24

1

Antigua and Barbuda

23

3

Timor-Leste

22

Botswana

20

1

Laos

19

Belize

18

2

Fiji

18

Malawi

17

2

Dominica

16

Namibia

16

Saint Kitts and Nevis

15

Saint Lucia

15

Curaçao

14

1

Grenada

14

Central African Republic

12

Saint Vincent and the Grenadines

12

Falkland Islands

11

Greenland

11

Montserrat

11

Seychelles

11

Turks and Caicos Islands

11

1

Gambia

10

1

Nicaragua

10

2

Suriname

10

1

Vatican City

9

Mauritania

7

1

Papua New Guinea

7

Western Sahara

6

Bhutan

5

British Virgin Islands

5

1

Burundi

5

1

South Sudan

4

São Tomé and Príncipe

4

Anguilla

3

Yemen

1

 

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Agencies
June 12,2020

Kabul, Jun 12: A blast in a mosque during Friday prayers in the western part of capital Kabul has killed at least four people and wounded many more, Afghanistan's interior ministry said.

"Explosives placed inside the Sher Shah Suri Mosque exploded during Friday prayers," said a statement issued by the ministry, which added that the mosque's prayer leader Mofleh Frotan was among those killed.

Interior ministry spokesman Tariq Arian said police have cordoned off the area and helped move the wounded to ambulances and nearby hospitals.

No group immediately claimed responsibility for the attack but a mosque attack earlier this month was claimed by an ISIL (or ISIS) group affiliate, headquartered in eastern Afghanistan's Nangarhar province.

"Interestingly, every time you have the peace process gaining some momentum and pace, you have these kinds of attacks in the country," Habib Wardak, a national security analyst based in Kabul, told Al Jazeera.

"The Islamic State group claimed responsibility for the attack that happened last week on a mosque in Kabul, so despite the fact that you have these news and press conference from the government that they have eliminated ISIL, how can they conduct such sophisticated operations?"

Friday's blast had parallels to one earlier this month, when an explosion tore apart a famous Kabul mosque and led to the death of renowned Afghan cleric Maulvi Ayaz Niazi.

"In this attack, the imam seems to be the target, not the rest of the crowd. These are the imams who have supported the peace process with the Taliban movement," Wardak said.

"The other political aspect for these kinds of attacks is that there are peace spoilers trying to convey a message that peace with the Taliban will not eradicate violence in the country because you have ISIL."

Violence has spiked in recent weeks in Afghanistan with most of the attacks claimed by the ISIL affiliate.

The United States blamed the armed group for a horrific attack last month on a maternity hospital in the capital that killed 24 people, including two infants and several new mothers.

The ISIL affiliate also took responsibility for an attack on a bus carrying journalists in Kabul on May 30, killing two.

It also claimed credit for an attack on the funeral of a strongman loyal to the government last month that killed 35 people.

Meanwhile, the US is attempting to broker peace talks between the Afghan government and the Taliban to end 18 years of war.

Washington's peace envoy Zalmay Khalilzad was in the region earlier this week trying to resuscitate a US peace deal with the Taliban.

The peace deal signed in February calls for the withdrawal of the US and NATO troops from Afghanistan in return for a commitment by the Taliban to not launch attacks on the US or its allies.

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News Network
May 15,2020

May 15: Global tensions simmered over the race for a coronavirus vaccine Thursday, as the United States and China traded jabs, and France slammed pharmaceuticals giant Sanofi for suggesting the US would get any eventual vaccine first.

Scientists are working at breakneck speed to develop a vaccine for COVID-19, the disease caused by the virus, which has killed more than 300,000 people worldwide and pummelled economies.

From the US to Europe to Asia, national and local governments are easing lockdown orders to get people back to work -- while fretting over a possible second wave of infections.

Increased freedom of movement means an increased risk of contracting the virus, and so national labs and private firms are labouring to find the right formula for a vaccine.

The European Union's medicines agency offered some hope when it said one could be ready in a year, based on data from clinical trials already underway.

But Marco Cavaleri, the EMA's head of vaccines strategy, acknowledged that timeline was a "best-case scenario," and cautioned that "there may be delays."

The race for a vaccine has exposed a raw nerve in relations between the United States and China, where the virus was first detected late last year in the central city of Wuhan.

Two US agencies warned Wednesday that Chinese hackers were trying to steal COVID-19 vaccine research -- a claim Beijing rejected as "smearing" its reputation.

US President Donald Trump, who has ratcheted up the rhetoric against China, said he doesn't even want to engage with Chinese leader Xi Jinping -- potentially imperilling a trade deal between the world's top two economies.

"I'm very disappointed in China. I will tell you that right now," he said in an interview with Fox Business.

"There are many things we could do. We could do things. We could cut off the whole relationship."

On Capitol Hill, an ousted US health official told Congress that the Trump government had no strategy in place to find and distribute a vaccine to millions of Americans, warning of the "darkest winter" ahead.

"We don't have a single point of leadership right now for this response, and we don't have a master plan," said Rick Bright, who was removed last month as head of the US agency charged with developing a coronavirus vaccine.

The United States has registered nearly 86,000 deaths linked to COVID-19 -- the highest toll of any nation.

World leaders were among 140 signatories to a letter published Thursday saying any vaccine should not be patented and that the science should be shared among nations.

"Governments and international partners must unite around a global guarantee which ensures that, when a safe and effective vaccine is developed, it is produced rapidly at scale and made available for all people, in all countries, free of charge," it said.

But a row erupted in France after drugmaker Sanofi said it would reserve first shipments of any vaccine it discovered to the United States.

The comments prompted a swift rebuke from the French government -- President Emmanuel Macron's office said any vaccine should be treated as "a global public good, which is not submitted to market forces."

Sanofi chief executive Paul Hudson said the US had a risk-sharing model that allowed for manufacturing to start before a vaccine had been finally approved -- while Europe did not.

"The US government has the right to the largest pre-order because it's invested in taking the risk," Hudson told Bloomberg News.

Macron's top officials are scheduled to meet with Sanofi executives about the issue next week.

The search for a vaccine became even more urgent after the World Health Organization said the disease may never go away and the world would have to learn to live with it for good.

"This virus may become just another endemic virus in our communities and this virus may never go away," said Michael Ryan, the UN body's emergencies director.

The prospect of the disease lingering leaves governments facing a delicate balancing act between suppressing the pathogen and getting their economies up and running.

In the US, more grim economic data emerged Thursday, with nearly three million more Americans applying for unemployment benefits.

That takes the overall total to 36.5 million -- more than 10 percent of the US population.

Further signs of the damage to businesses emerged when Lloyd's of London forecast the pandemic will cost the global insurance industry about $203 billion.

European markets closed down, but Wall Street rallied despite the new jobless claims. In a sign of progress, the New York Stock Exchange trading floor was due to reopen on May 26.

The reopening of economies continued in earnest across Europe, where the EU has set out proposals for a phased restart of travel and the eventual lifting of border controls.

"Maybe it's a mistake, but we have no choice. Without tourists, we won't get by!" Enrico Facchetti, a 61-year-old former goldsmith, said of Venice's reopening.

Japan -- the world's third largest economy -- lifted a state of emergency across most of the country except for Tokyo and Osaka.

And Canadian Prime Minister Justin Trudeau said national parks would partially reopen on June 1.

But in Latin America, the virus continued to surge, with a 60 percent leap in cases in the Chilean capital of Santiago.

Authorities said 2,000 new graves were being dug at the main cemetery.

South Sudan reported its first COVID-19 death on Thursday.

And in Bangladesh, the first case was confirmed in the teeming Rohingya refugee camps in Bangladesh, which are home to nearly one million people.

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