May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Chaddis gone Pantloons came, Notes gone Faku Notes started, Bap ray Bap what's happening these Criminal Looters ruling, Master Narean Where are you???? now do not come front, let it dissolve all these note dealings after we will see how it works!!!!!
Subbu, Mangalore,
That app is only for fun. Not for scanning the currency. It does work even on a xerox copy of new Rs.2000 note.
Need to keep an eye on BANGHI PARIVAR.
What Bhakts said and what happened ?
1] Demonetization will stop fake currency circulation.
- Fake currency starts off from their favourite United States of Gujarath and goes across the country.
2] It will stop terrorists funding.
- 3 terrorists held with the New Rs. 2000 note currency, while poor still stand in long queues at banks.
3] Black money will be stopped and black money holders will be jailed.
- SBI waives off loans of more than 50 loan defaulters including Vijay mallya.
4] Demonetization will boost economy
- All markets affected due to lack of sales activities in the past 2 weeks.
- Dollar is higher than ever at Rs. 68.14/ USD.
5] 15 Lakhs will surely com into ur account.
- Government takes people's own hard earned money to fee the crony capitalists, even at the cost of 56 people's death till today.
Mistron, Acche Din Aagaye, ab phir ek bar BJP sarkar
All thanks to Fenku.
This is the trap played by the liquor shop .....
It seems like Bantwal is notorious for fake currencies.....need to keep an eye on it by security system....
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