May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Kill them whenever they enter your home, there is no punishment for self defense... Judiciary is permit you to kill any person or group if they enter your home forcefully...next time don't give them a chance to escape alive...
BJP has lost its civic sense,how can they rule the country? if they cannot respect senior citizens. Intolerance has reached its peak amongst BJP. Curse of these senior citizens will lead them to their dooms day in sha Allah.They should not forget that human is mortal
BJP is a sore loser
Where is Ibraheem Hussain Udupi
Where is CongRSS ? are Siddanna,Paramesh appa, rammnna ?
COWARDS Since the time of BRITIISH, Either supporting the british against indian independence or attack cowardly 100 X 1 or 3
Animal is animal (do they ask people to worship them or use it to celebration)
Please publish news about BJP MP Statement
Terrorism will not destroy without ending Islam
Let people come to know about elected candidate work progress
Guys election is over, accept the reality and work together for the betterment of poor and downtrodden people. But police do their job and nab those who are responsible for attacking old age persons and destroying their properties....this is really bad...
Really very much condemnable, but how much you reported that , we Hindustanis non believable movement attacking the Woman, totally Criminalizes, Goonda act non bail Black Prison Inside, These BJP,RSS Criminal Goondas so far not attacked women their Plan only make Problem for Looting, the biggest Looters, Thieves are BJP/RSS Goondas and Criminals, looks like now in Karnataka in Siddannas Government they can not do their Criminalize, path were these Criminals ruling.
\\"but one thing Every Dog has its own Day Anna\"
Jia Hindustan."
Acche din
This is a time to ban BJP/RSS terrorist group and kicking them out of the country
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