May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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poojareln yenchala lagadi dethha nana hindulene lagadi deppna bodcchi
SDPI supporters please stay away from BJP and JDS.
Because of SDPI's poor decission to run in the previous election BJP won
Congress lost (because Muslim votes got divided between SDPI and Congress.
This time be smart and vote for Congress.
Was your father wakil ? Stfu
Nikkla onji try malpoli.......
they have done good and healthy wedding...what about your shiroor swamiji, he sold his soul to BJP the worst party of india only fraud and evil people will join..
SDPI will not do any illigale and damage to our socity also they will not tigh with CongRSS,they need to avoide to come terorist BJP to win in bantwal ,in this reason SDPI with draw nomination,but sense less you went with BJP with extra marital affair, sham on you sham on your party.
Wa wonder to wonderfull said Khazi Hariram Krishna, best of best luck 'Khazi Hari" good award to you, Thousand Congratulatations keep it Anna do not be a Jeloues!!!! you were luckey to get this award, Shobakka remaining Vacated are you happy go ahead the Ramanathanna to carry out as a Priest to conduct the ceremony!!! If akka willl willed, otherwise you go north to find this age very difficult, there are in our south Indian custems to you no chance accept Akka.
Good luck Khazi Hariramanna
Jai hoo Ramanathanna
Jai Hoo Akkamma akka
I think Harikrishna Bantwal was the Khazi for this secret wedding. But am worried whether the bride will ditch the hubby by secretly going for honeymoon with the BJP.
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