Salt tied to elevated blood pressure, even with healthy diet, says study

Agencies
March 7, 2018

People who eat lots of fruits, veggies, and whole grains may still have an increased risk of elevated blood pressure if they consume a lot of salt, a new study suggests.

Eating high-sodium foods has long been associated with raised blood pressure readings, but some evidence suggests that body weight and other nutrients in the diet may modify or offset the effects of sodium on blood pressure.

To see how diet might influence the connection between salt and blood pressure, researchers examined data from food surveys completed by 4,680 middle-aged adults, and determined the amount of 80 nutrients in each person’s diet.

With the exception of potassium, none of these nutrients appeared to weaken the connection between eating a high-sodium diet and having higher average blood pressure readings over 24 hours than people who ate the least sodium, researchers report in Hypertension.

“This matters because it indicates that the problem of excess salt intake and its adverse effects on blood pressure cannot be solved by augmenting the diet with other nutrients,” said lead study author Dr. Jeremiah Stamler of the Feinberg School of Medicine at Northwestern University in Chicago.

“The solution is reduction in salt intake,” Stamler said. “This is difficult since, as a result of commercial food processing, salt is almost everywhere in the food supply.”

Chronic high blood pressure is tied to an increased risk of heart disease, heart attack, stroke and heart failure.

To lower the risk of heart disease, adults should reduce sodium intake to less than 2 grams a day, or the equivalent of about one teaspoon of table salt, according to the World Health Organization (WHO).

Sodium is found not only in salt, but also in a variety of foods such as bread, milk, eggs, meat and shellfish as well as processed items like soup, pretzels, popcorn, soy sauce and bouillon cubes.

Extra sodium in the bloodstream can pull water into the blood vessels and boost blood pressure by increasing the amount of fluid the heart needs to pump through the body. Potassium can help remove excess sodium from the body.

In the current study, researchers examined data on sodium and potassium levels in urine, as well as blood pressure, height, weight and eating habits from adults aged 40 to 59 in Japan, China, the UK and the US

Higher sodium levels were associated with elevated blood pressure for both men and women at all ages in the study, regardless of race and ethnicity or socioeconomic status.

The connection between sodium and blood pressure was similarly strong for both normal weight and obese people in the study, although the connection was weaker for overweight individuals who weren’t obese.

Potassium appeared to weaken the connection between dietary salt and elevated blood pressure only for people who had low sodium levels in their urine, the researchers also found.

The study wasn’t a controlled experiment designed to prove whether or how dietary salt or other things people eat might directly alter blood pressure. Another limitation is that surveys used to assess eating habits can be unreliable snapshots of what people actually consume.

Even so, the results add to evidence that managing blood pressure requires paying attention to salt, said Cheryl Anderson, a researcher at the University of California San Diego School of Medicine who wasn’t involved in the study.

“Even though potassium can help lessen the blood pressure-raising effects of sodium, eating more potassium isn’t a license to eat more sodium,” Anderson said.

The American Heart Association recommends the Dietary Approaches to Stop Hypertension (DASH) diet or a Mediterranean-style diet to help prevent cardiovascular disease. Both diets emphasize cooking with vegetable oils with unsaturated fats, eating nuts, fruits, vegetables, low-fat dairy products, whole grains, fish and poultry, and limiting red meat and added sugars and salt.

“There is data showing that when the DASH dietary pattern is combined with sodium reduction there are substantial effects on blood pressure,” Anderson said. “This can be as powerful as taking a drug prescription for high blood pressure.”

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Agencies
August 2,2020

Washington, Aug 2: Children under the age of five have between 10 to 100 times greater levels of genetic material of the coronavirus in their noses compared to older children and adults, a study in JAMA Pediatrics said Thursday.

Its authors wrote this meant that young children might be important drivers of Covid-19 transmission within communities -- a suggestion at odds with the current prevailing narrative.

The paper comes as the administration of US President Donald Trump is pushing hard for schools and daycare to reopen in order to kickstart the economy.

Between March 23 and April 27, researchers carried out nasal swab tests on 145 Chicago patients with mild to moderate illness within one week of symptom onset.

The patients were divided into three groups: 46 children younger than five-years-old, 51 children aged five to 17 years, and 48 adults aged 18 to 65 years.

The team, led by Dr Taylor Heald-Sargent of the Ann & Robert H. Lurie Children's Hospital, observed, "a 10-fold to 100-fold greater amount of SARS-CoV-2 in the upper respiratory tract of young children."

15 countries with the highest number of cases, deaths due to the Covid-19 pandemic

The authors added that a recent lab study had demonstrated that the more viral genetic material was present, the more infectious virus could be grown.

It has also previously been shown that children with high viral loads of the respiratory syncytial virus (RSV) are more likely to spread the disease.

"Thus, young children can potentially be important drivers of SARS-CoV-2 spread in the general population," the authors wrote.

"Behavioral habits of young children and close quarters in school and daycare settings raise concern for SARS-CoV-2 amplification in this population as public health restrictions are eased," they concluded.

The new findings are at odds with the current view among health authorities that young children -- who, it has been well established, are far less likely to fall seriously ill from the virus -- don't spread it much to others either.

However, there has been fairly little research on the topic so far.

One recent study in South Korea found children aged 10 to 19 transmitted Covid-19 within households as much as adults, but children under nine transmitted the virus at lower rates.

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Agencies
July 7,2020

The World Health Organization (WHO) is reviewing a report that suggested its advice on the novel coronavirus needs updating after some scientists told the New York Times there was evidence the virus could be spread by tiny particles in the air.

The WHO says the Covid-19 disease spreads primarily through small droplets, which are expelled from the nose and mouth when an infected person breaths them out in coughs, sneezes, speech or laughter and quickly sink to the ground.

In an open letter to the Geneva-based agency, 239 scientists in 32 countries outlined the evidence they say shows that smaller exhaled particles can infect people who inhale them, the newspaper said on Saturday.

Because those smaller particles can linger in the air longer, the scientists - who plan to publish their findings in a scientific journal this week - are urging WHO to update its guidance, the Times said.

"We are aware of the article and are reviewing its contents with our technical experts," WHO spokesman Tarik Jasarevic said in an email reply on Monday to a Reuters request for comment.

The extent to which the coronavirus can be spread by the so-called airborne or aerosol route - as opposed to by larger droplets in coughs and sneezes - remains disputed.

Any change in the WHO's assessment of the risk of transmission could affect its current advice on keeping one-metre physical distancing. Governments, which also rely on the agency for guidance policy, may also have to adjust public health measures aimed at curbing the spread of the virus.

"Especially in the last couple of months, we have been stating several times that we consider airborne transmission as possible but certainly not supported by solid or even clear evidence," Benedetta Allegranzi, the WHO's technical lead for infection prevention and control, was quoted as saying in the New York Times.

WHO guidance to health workers, dated June 29, says that SARS-CoV-2, the virus that causes Covid-19, is primarily transmitted between people through respiratory droplets and on surfaces.

But airborne transmission via smaller particles is possible in some circumstances, such as when performing intubation and aerosol-generating procedures, it says.

Medical workers performing such procedures should wear heavy-duty N95 respiratory masks and other protective equipment in an adequately ventilated room, the WHO says.

Officials at South Korea's Centers for Disease Control said on Monday they were continuing to discuss various issues about Covid-19, including the possible airborne transmission. They said more investigations and evidence were needed.

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Agencies
July 8,2020

Probiotics that broaden the mix of helpful bacteria in the gut may help to ease depression, say researchers.

Foods that broaden the profile of helpful bacteria in the gut are collectively known as probiotics. These "good bacteria" can be taken as supplements, or found naturally in yoghurts or fermented foods.

For the findings, the research team from the University of Brighton in the UK searched for relevant studies published in English between 2003 and 2019, which looked at the potential therapeutic contribution of pre-and probiotics in adults with depression and/or anxiety disorders.

Out of an initial haul of 71 studies, just seven met all the criteria for inclusion. All 7 investigated at least one probiotic strain; four looked at the effect of combinations of multiple strains.In all, 12 probiotic strains featured in the selected studies, primarily Lactobacillus acidophilus, Lactobacillus casei, and Bifidobacterium bifidium.

One study looked at combined pre-probiotic treatment, while one looked at prebiotic therapy by itself. The studies varied considerably in their design, methods used, and clinical considerations, but all of them concluded that probiotic supplements either alone or in combination with prebiotics may be linked to measurable reductions in depression.

And every study showed a significant fall or improvement in anxiety symptoms and clinically relevant changes in biochemical measures of anxiety or depression with probiotic or combined pre-probiotic use.

Of the 12 different probiotics investigated, 11 were potentially useful, the findings showed.'Probiotics may help reduce the production of inflammatory chemicals, such as cytokines, as is the case in inflammatory bowel disease, the researchers suggested.

"They may help direct the action of tryptophan, a chemical thought to be important in the gut-brain axis in psychiatric disorders," they added.

In this way, with a better understanding of the mechanisms, probiotics may prove to be a useful tool across a wide range of conditions," the authors wrote.

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