Thai king Adulyadej dies after 7-decade long reign

Beijing:  Around 5,000 people have signed up for the phase I clinical trial of recombinant novel coronavirus vaccine in Chinese city Wuhan where the virus first emerged late last year.

The recruitment for participants ended this week with nearly 5,000 volunteers signing up for the trial, state-run Beijing News reported on Wednesday.

A single-centre, open and dose-escalation phase I clinical trial for recombinant novel coronavirus vaccine (adenoviral vector) will be tested in healthy adults aged between 18 and 60 years, according to the ChiCTR (China Clinical Trial Register).

The trial, led by experts from the Academy of Military Medical Sciences, gained its approval on March 16 and the research is expected to last half a year.

Requiring at least 108 participants, the trial will be conducted in Wuhan, capital of Hubei province, the region worst-affected by the virus in the country, state-run China Daily reported.

Participants will experience 14-day quarantine restrictions after being vaccinated and their health condition will be recorded every day.

Chinese scientists are hastening the development of COVID-19 vaccines through five approaches --- inactivated vaccines, genetic engineering subunit vaccines, adenovirus vector vaccines, nucleic acid vaccines and vaccines using attenuated influenza virus as vectors.

So far, most teams are expected to complete preclinical research in April and some are moving forward faster, Wang Junzhi, an academician with the Chinese Academy of Engineering said.

Wang noted that research and development of COVID-19 vaccines in China is not slower than foreign counterparts and has been carried out in a scientific, standardised and orderly way.

China has stepped up the process to finalise vaccines to counter COVID-19 after Kaiser Permanente research facility in Seattle and Washington stole the march and began human trials.

China lifted tough restrictions on the Hubei province on Wednesday after a months-long lockdown as the country reported no new domestic cases.

But there were another 47 imported infections from overseas, the National Health Commission said. In total, 474 imported infections have been diagnosed in China -- mostly Chinese nationals returning home.

Los Angeles, Apr 30: Los Angeles will begin offering coronavirus">coronavirus testing for free to all citizens regardless of whether they have symptoms, Mayor Eric Garcetti said on Wednesday, adding that LA is the first major US city to take such an initiative.

During the press conference, Garcetti announced that all county residents can now get free coronavirus">coronavirus testing. 

He said the announcement will only apply to city residents for now, but that a similar plan is in development for Los Angeles County,
Garcetti also took to Twitter to announce the same. "Announcing that L.A. is now the first major city in America to offer free COVID-19 testing to all residents. 

While priority will still be given to those with symptoms, individuals without symptoms can also be tested. Sign up at Coronavirus.LACity.org/Testing," he said
Under the new guidelines, priority for the same- or next-day testing will still be given to people with symptoms, such as a fever, cough, and shortness of breath. The free testing will also be prioritized for certain critical frontline workers who interact with the public.

Until now, only residents with symptoms as well as essential workers and those in institutional settings like nursing homes could be tested.

On Wednesday, the LA County reported 1,541 new cases, bringing the total to 22,485 - a seven per cent increase since yesterday.

This includes a backlog of cases that were processed. In the city, there were 683 new cases on Wednesday, bringing the total to 10,380 -- a 7 percent increase since yesterday.

Minneapolis, Jun 2: An official autopsy released Monday ruled that George Floyd, the African-American man whose death at police hands set off unrest across the United States, died in a homicide involving "neck compression".

George, 46, died of "cardiopulmonary arrest complicating law enforcement subdual, restraint, and neck compression," and the manner of death was "homicide," the Hennepin County Medical Examiner in Minneapolis said in a statement.

Floyd's other significant health conditions were listed as "arteriosclerotic and hypertensive heart disease; fentanyl intoxication; recent methamphetamine use."

The statement added that the "manner of death is not a legal determination of culpability or intent."

It emphasized that under Minnesota state law "the Medical Examiner is a neutral and independent office and is separate and distinct from any prosecutorial authority or law enforcement agency."