May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Naren....do a candle March for you cow maa first....then bharat maa....ha ha........we will be there in kadri....you will be repeating your bla bla.....sanghi paid goon....shitting in Singapooor.....poor fellow modiji can't help him to find a job here...what a pity in the bmj...chanters....
One Pakistani rant started chanting porkis slogan ...le farooq ....your kashmiri civilians who were killed are jihadis ... They shout anti India slogan ..sorry we dont consider them as indians at slll . they want benefits from India and loyalty to Pakistan ...any person who is born to their fathers will not support kashmiri stone Pelters ...nange doubt nin mele hahaha ..Kashmir belongs to indian nationalist ...bholo bharath mata ki jai ...no of unlikes shows this media is filled with pakis
Uri terror attack should be condemned and the wrong doers should be punished. But this brutal act did not happen all of a sudden. It was part of the two month long violence in Kashmir which killed nearly hundred people and injured thousands of innocent Kashmiris.
When you show solidarity with martyred soldiers, you should not forget the martyred Kashmiri civilians. Only terrorists deserve death. Civilians deserve your solidarity and those who are using pellet guns against innocent civilians deserve punishment.
United for a better Mangaluru now expanded jurisdiction till district borders? Or this is a new forum?
Lets join our hands together to support our armed forces that are protection our nation by sacrifying lives.
Btw, why caostaldigst.com did not cover yesterday's event at the same Kadri War Memorial wherein nationalist leaders paid tributes to the martyrs?
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