4 killed as Dalits crushed under tractors, women thrashed in violence over land dispute in Rajasthan

New Delhi, Jul 6: The Indian Academy of Sciences, a Bengaluru-based body of scientists, has said the Indian Council for Medical Research's (ICMR) target to launch a coronavirus vaccine by August 15 is "unfeasible" and "unrealistic".

The IASc said while there is an unquestioned urgent need, vaccine development for use in humans requires scientifically executed clinical trials in a phased manner.

While administrative approvals can be expedited, the "scientific processes of experimentation and data collection have a natural time span that cannot be hastened without compromising standards of scientific rigour", the IASc said in a statement.

In its statement, the IASc referred to the ICMR's letter which states that "it is envisaged to launch the vaccine for public health use latest by 15th August 2020 after completion of all clinical trials".

The ICMR and Bharat Biotech India Limited, a private pharmaceutical company, are jointly developing the vaccine against the novel coronavirus -- SARS-CoV-2.

The IASc welcomes the exciting development of a candidate vaccine and wishes that the vaccine is quickly made available for public use, the statement said.

"However, as a body of scientists including many who are engaged in vaccine development IASc strongly believes that the announced timeline is unfeasible. This timeline has raised unrealistic hope and expectations in the minds of our citizens," it said.

Aiming to launch an indigenous COVID-19 vaccine by August 15, the ICMR had written to select medical institutions and hospitals to fast-track clinical trial approvals for the vaccine candidate, COVAXIN.

Experts have also cautioned against rushing the process for developing a COVID-19 vaccine and stressed that it is not in accordance with the globally accepted norms to fast-track vaccine development for diseases of pandemic potential.

The IASc said trials for a vaccine involve evaluation of safety (Phase 1 trial), efficacy and side effects at different dose levels (Phase 2 trial), and confirmation of safety and efficacy in thousands of healthy people (Phase 3 trial) before its release for public use.

Clinical trials for a candidate vaccine require participation of healthy human volunteers. Therefore, many ethical and regulatory approvals need to be obtained prior to the initiation of the trials, it added.

The IASc said the immune responses usually take several weeks to develop and relevant data should not be collected earlier.

"Moreover, data collected in one phase must be adequately analysed before the next phase can be initiated. If the data of any phase are unacceptable then the clinical trial is required to be immediately aborted," it said.

For example, if the data collected from Phase 1 of the clinical trial show that the vaccine is not adequately safe, then Phase 2 cannot be initiated and the candidate vaccine must be discarded.

For these reasons, the Indian Academy of Sciences believes that the announced timeline is "unreasonable and without precedent", the statement said.

"The Academy strongly believes that any hasty solution that may compromise rigorous scientific processes and standards will likely have long-term adverse impacts of unforeseen magnitude on citizens of India," it said.

Puducherry, Jan 5: Puducherry Lt Governor Kiran Bedi, a former IPS officer, became the butt of Twitterati jokes on Saturday after she tweeted that NASA recording of the sound of the sun was in fact 'Om' chant. She wrote at @thekiranbedi: "NASA recorded sound of the sun -- Sun chants Om."

pic.twitter.com/ArRwljjDVE

— Kiran Bedi (@thekiranbedi) January 4, 2020

The post got 5.6K retweets and 17.7K likes, and as many as 472.6K views.

One user remarked: "Wrong. The Sun said NaMo NaMo. You should've checked the UNESCO version along with the NASA version."

A post read: "And we thought you were intelligent."

One user posted a picture of Kiran Bedi with Sadhguru Jaggi who was trolled a few days ago after he posted his support on the Citizenship Amendment Act. He commented: "This picture can be provided."

A Twitter user reminded the former bureaucrat about the Indian Constitution's Fundamental Duties (Article 51A) that says that it shall be the duty of every citizens of India to develop scientific temper, humanism and the spirit of inquiry and reform.

Another wondered aloud: "We don't know how you cleared the Civil Services exams. We are ashamed...."

A user posted a clip of a well known stand-up comic who talked about the celestial hum which many claim to be Om chant.

A post read: "I consider this tweet by you as one of the best jokes of the millennium. The saffron brigade is successful in brainwashing learned people like you."
One user commented: "Once upon a time this lady was a hero to many. What a disgrace now!"

Thiruvananthapuram, Apr 9: Kerala, which was among the first state in the country to report a Corona positive case, has turned its entire public healthcare system into a single interconnected grid to generate uninterrupted information and provide flawless services, thanks to the daily zoom or video conferences of top health authorities for chalking out a dynamic strategy to tackle the COVID-19 pandemic.

The daily zoom or remote conferences held by Health Minister K K Shailaja and top health sector officials with the medical and paramedical personnel on the ground have lent a cutting edge to the state government’s all out efforts in monitoring the situation on the ground and formulating effective responses to address the various needs and concerns of the people, an official release said on Thursday.

The Minister is joined in this meticulous exercise by top administrators and planners, including Dr Rajan N Khobragade, Principal Secretary, Health; Dr. Rathan U Kelker, State Mission Director, National Health Mission, Dr Saritha, Director of Health Services, Dr Ramla Beevi, Director of Medical Education and other senior officials.