New Delhi, Jul 6: The Indian Academy of Sciences, a Bengaluru-based body of scientists, has said the Indian Council for Medical Research's (ICMR) target to launch a coronavirus vaccine by August 15 is "unfeasible" and "unrealistic".
The IASc said while there is an unquestioned urgent need, vaccine development for use in humans requires scientifically executed clinical trials in a phased manner.
While administrative approvals can be expedited, the "scientific processes of experimentation and data collection have a natural time span that cannot be hastened without compromising standards of scientific rigour", the IASc said in a statement.
In its statement, the IASc referred to the ICMR's letter which states that "it is envisaged to launch the vaccine for public health use latest by 15th August 2020 after completion of all clinical trials".
The ICMR and Bharat Biotech India Limited, a private pharmaceutical company, are jointly developing the vaccine against the novel coronavirus -- SARS-CoV-2.
The IASc welcomes the exciting development of a candidate vaccine and wishes that the vaccine is quickly made available for public use, the statement said.
"However, as a body of scientists including many who are engaged in vaccine development IASc strongly believes that the announced timeline is unfeasible. This timeline has raised unrealistic hope and expectations in the minds of our citizens," it said.
Aiming to launch an indigenous COVID-19 vaccine by August 15, the ICMR had written to select medical institutions and hospitals to fast-track clinical trial approvals for the vaccine candidate, COVAXIN.
Experts have also cautioned against rushing the process for developing a COVID-19 vaccine and stressed that it is not in accordance with the globally accepted norms to fast-track vaccine development for diseases of pandemic potential.
The IASc said trials for a vaccine involve evaluation of safety (Phase 1 trial), efficacy and side effects at different dose levels (Phase 2 trial), and confirmation of safety and efficacy in thousands of healthy people (Phase 3 trial) before its release for public use.
Clinical trials for a candidate vaccine require participation of healthy human volunteers. Therefore, many ethical and regulatory approvals need to be obtained prior to the initiation of the trials, it added.
The IASc said the immune responses usually take several weeks to develop and relevant data should not be collected earlier.
"Moreover, data collected in one phase must be adequately analysed before the next phase can be initiated. If the data of any phase are unacceptable then the clinical trial is required to be immediately aborted," it said.
For example, if the data collected from Phase 1 of the clinical trial show that the vaccine is not adequately safe, then Phase 2 cannot be initiated and the candidate vaccine must be discarded.
For these reasons, the Indian Academy of Sciences believes that the announced timeline is "unreasonable and without precedent", the statement said.
"The Academy strongly believes that any hasty solution that may compromise rigorous scientific processes and standards will likely have long-term adverse impacts of unforeseen magnitude on citizens of India," it said.
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This muslim lady is lucky that Police only asked her to remove burqa and did not force her to wear bhagwa color saree and put tilak on her forehead as per bjp manifesto. She is also lucky that bjp backed police did not label her to be from Bangladesh. Shame on you sister for joining anti muslim and anti national Bjp. They will never accept you as Indian. Tomorrow they will say that the house you are staying was a mandir and will drag you out of it.
why she removed her burqa? it is better for her to leave the program instead of removing burqa.
She is BJP worker then she can complaint this with her party chiefs to take action on police, otherwise will leave the party.
It is not compulsory for her to attend that meeting.
What a shame, disastrous. so this is what the new India(___ Rashtriya) will be? What do the people want to do with mahatma Gandhi’s version of India? You want to change it to savatkers version? the guy who wrote mercy potions to British , who was against freedom and was aggressively against Indian flag.
Its shame. so book of thoughts (RSS book) is right leave as per yogi’s disturbed mentality’s requirement or give your neck to his sword?
Shame. People have fallen pray to the conspiracy making them feel they are insecure by handful 18% population.
“she is a BJP party worker”
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