May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Comments
Must be somebody from the HJV killed him to make it look like suicide. are the police investigating. All unnatural deaths should be properly checked.
Brother Manish #1
You have Mistaken What is the use of Organisation when Almighty Allah is not with them.
Learn Islam before its too late.
Naren and viren are busy with preparing CD/video to misuse this situation to frame some innocent people and trap them with Gooswami.
Our nationalist peddu naren is commenting on other news but he is not here with his brother? thats so sad when someone needs condolence he is not here... thats a shame for him and his HJV or HIV
Hi.. your goggles are super!!! how much u paid? now who using them?
Sad to know that there are people who celebrate the untimely death of a youth. #RIP humanity.
RIP, Any way great job, this is the lesson for youth of bajarangi what happens if cancer is in your mind
Entire organisation would be with you if you attacked Muslims or Christians. I bet if you consulted minorities regarding your problem you would be alive today.. RIP.. We know one to blame but what HJV are doing with minorities entire country knows.. And don't forget Manish... God is above any organisation..
And this kind of people lead organizations.....come on.....bhudhanaazhcha ka nahee to kyaa public ka
Feenari........
Madidunno maraya!!
I don't agree with Manish's comments
Had your entire organisation was with him this wouldn't have happened
All such org only uses such youths and make public bakra
RIP brother. You took a wrong step when entire organisation was with you.
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