May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
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Inna lillahi va inna ilaihi rajioon
he was a great person
May Allah grant him Jannah
may Allah forgive his sins if any
May Allah make Grave lightfull
Heartfelt condolences from Zakria family in Qatar.
May Allah bless him with jannathul firdaus.
Inna lillahi wa Inna ilaihi rajivoon..
m heartiest condolence to the families of maulana mohamed shafie
Inna lillahi wa inna ilayhi raji'un
Inna lillahi wa inna ilahi raji'un
INNA LILLAHI WA INNA ILAHI RAJI'UN
Innalillahi Wa inna Ilahirrajiwoon.
Inna Lillahi wa inna Ilaihi rajioon
Allahummghfirlahu warhamhu, wa aafihim wa'afa anhu!
warzuq'hum Jannathul Firdowse al A'ala
Innalillahi Wa inna ilaihi rajiooon
May allah grant him jannatul firdouse,,,
Ameen...
May Allah grant him paradise and give us death while He is pleased with us.
\To Allah we belong and to him we return\". Indeed! Whatever Allah give or take belongs to him and everything is predestined by him-Prophet Mohammad (PBUH)."
Inna lillah wa inna ilaihi rajiwoon. May allah acceipt his all good deeds and grant him Jannaah.
Aameen
Inna lillahi wa inna ilaihi rajioon
May Almighty Accept all his good deeds
Ameen
Inna Lillaahi wa inna ilaihi raajihoon. Allaahummgfirlahoo warhamhoo wahfu anhu yaa Rabbal Aalameen. ameen.
Innaa Lillahi Wa Innaa Ilaihi Rajivoon. We are from Allah and to HIM we return.
Maulana Ebrahim Muhammed Shafi Saheb is a proud father of professionals in the field of Journalism, Enterpreneurship, Administration and philanthrophy Al-Hamdulillah.
May the departed soul rest in peace. May Allah bless him with the bounties of Jannah and May Allah give sabr (patience) to the grieved family to bear the loss of their dear one.
Heartfelt condolences.
Inna lillahi wa inna ilayhi raji'un
Inna lillahi wa inna ilayhi raji'un
Inna lillahi wa inna ilahi rarji'un
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