May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.
According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.
"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.
They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.
Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.
"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.
"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.
In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.
"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.
The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.
These children were then confirmed to have COVID-19.
While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.
Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.
According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.
"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.
Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.
While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.
However, he cautioned that more research is needed to confirm their findings.
"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.
Police have launched a hunt for Mohammed Shahnawaz, a student of Milagres Collge, who went absconding after thrashing Rev Fr Michael Santumayar, the principal of the same college, near his chamber on Thursday for denying him hall ticket on grounds of attendance shortage.
Comments
he should be hanged ,
This boy who assaulted the Principal should be given the severest punishment - a lesson to all not to think of such crime in their dream also. However, some BORN dirty filthy generation of people brought religion here. These scums forgot what their religion is - Who raped Tulsmi Mata, who kidnapped Rukmini, Who killed Sambhuka, why they push the widow to burning fire, one girl is married to one brother - the rest of male start sharing her why??? Why wife's sister is half wife and husband's brother is half-husband to you - Why do you force Dalit women pray naked? Are you animals or worse than them??
action is to be condemned , but sensible people will not bring religion into this. This Boy will be put in jail shortly and punished as per IPC.
It is in his blood...so what else we can expect....they don't give respect for women ...for them women means property....even don't teach sanskar ...just they train how to steal, stab and cheat ...once they reach adulthood they get him bike and hanky panky shirts and pants. One apple iPhone ...next day these guys will be on jihad in front of colleges with sole aim of increasing population. ..why this community never produces quality world class scientists .this is the main reason .
@Sangeet
completely agree with your thoughts. I pray Almighty Allah to guide you to adopt the teachings of the religion of peace.
Ladies n gentlemen... don't bring religion for individuals action... shame on u ppl for vomiting venom on a particular religion whenever u get opportunity.... anyway these kinds of ur negative propoganda never let down Islam rather its spreading rapidly.
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