New Delhi amongst top cities where hearing is most degraded

March 5, 2017

Washington D.C, Mar 5: Urban noise pollution and hearing loss are closely linked, according to rankings of 50 large cities in both categories released on Friday.cars

High-decibel urban areas-such as Guangzhou, New Delhi, Cairo and Istanbul-topped the list of cities where hearing was most degraded, researchers reported.

Likewise, cities least afflicted by noise pollution-including Zurich, Vienna, Oslo and Munich-registered the lowest levels of decline in hearing.

This statistical link does not necessarily mean the constant din of city life is the main driver of hearing loss, which can also be caused by infections, genetic disorders, premature birth, and even some medicines.

The findings are also preliminary, and have yet to be submitted for peer-reviewed publication.

"But this is a robust result," said Henrik Matthies, managing director of Mimi Hearing Technologies, a German company that has amassed data on 200,000 people drawn from a hearing test administered via cell phones.

"The fact that noise pollution and hearing loss have such a tight correlation points to an intricate relationship," he told AFP.

Researchers at Mimi and Charite University Hospital in Berlin explored the link by constructing two separate databases.

The first combined information from the World Health Organization (WHO) and Norwegian-based technology research group SINTEF to create a noise pollution ranking for cities around the world.

Stockholm, Seoul, Amsterdam and Stuttgart were also among the least likely to assault one's ears, while Shanghai, Hong Kong and Barcelona came out as big noise makers.

Paris-one of the most densely populated major cities in Europe-scored as the third most cacophonous.

The ranking for hearing loss drew from Mimi's phone-based test, in which respondents indicated age and sex. Geo-location technology pinpointed the cities.

The results were measured against a standard for age-adjusted hearing.

On average, people in the loudest cities were ten years "older"-in terms of hearing loss-than those in the quietest cities, the study found.

Stacked side-by-side, the two city rankings are remarkably similar, suggesting more than an incidental link.

The findings highlight the need for better monitoring, the researchers said.

"While eye and sight checks are routine, ear and hearing exams are not," said Manfred Gross, head of the department of Audiology and Phoniatrics at Charite University Hospital.

"The earlier hearing loss is detected, the better the chances are for preventing further damage."

Collaborations between scientists and private companies that collect health-related information from consumers are becoming more common in the era of Big Data.

California-based DNA genetic testing company 23andMe, for example, has worked extensively with university researchers to ferret out rare genetic disorders by combing through mountains of anonymous data from its clients.

Also on Friday, World Hearing Day, the WHO released figures showing annual costs of unaddressed hearing loss of between $750 billion and $790 billion globally.

Direct health care costs were calculated to be up to $107 billion, with loss of productivity due to unemployment or early retirement about the same.

"Societal costs"-stemming from social isolation, inability to communicate and stigma-were estimated at more than $500 billion.

In a recent editorial, the medical journal The Lancet said hearing loss is a "silent epidemic", noting that proper care remains out of reach for millions of people.

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Agencies
February 6,2020

Researchers have found the rates of lung cancer are higher in young women than men.

The study, published in the journal Pediatrics, examined lung cancer rates in young adults in 40 countries across five continents and uncovered a trend of higher lung cancer rates in women compared with men in recent years.

The emerging trend was widespread, affecting countries across varied geographic locations and income levels.

The changes appeared to be driven by a rising rate of adenocarcinoma lung cancer among women, said the study researchers from University of Calgary in Canada.

Lung cancer rates have been higher among men than women because men started smoking in large numbers earlier and smoked at higher rates; however, recent studies have reported converging lung cancer incidence rates between sexes.

Among men, age specific lung cancer incidence rates generally decreased in all countries, while in women the rates varied across countries with the trends in most countries stable or declining, albeit at a slower pace compared to those in men.

For the findings, lung and bronchial cancer cases between 30-64 age group from 1993-2012 were extracted from cancer incidence in five continents.

The study found the higher emerging rates of lung cancer in young women compared to young men.

According to the researchers, future studies are needed to identify reasons for the elevated incidence of lung cancer among young women.

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Agencies
April 17,2020

Washington DC, Apr 17: In recent research, scientists have linked the emotional, social and psychiatric problems in children and adolescents with higher levels of genetic vulnerability for adult depression. The study implies that the genetics passed from parents may be linked with psychiatric problems in children and adolescents and may also leading to depression in adults.

University of Queensland scientists made the finding while analysing the genetic data of more than 42,000 children and adolescents from seven cohorts across Finland, the Netherlands, Norway, Sweden and the UK.

Professor Christel Middeldorp said that researchers have also found a link with a higher genetic vulnerability for insomnia, neuroticism and body mass index.

"By contrast, study participants with higher genetic scores for educational attainment and emotional well-being were found to have reduced childhood problems," Professor Middeldorp said.

"We calculated a person's level of genetic vulnerability by adding up the number of risk genes they had for a specific disorder or trait and then made adjustments based on the level of importance of each gene We found the relationship was mostly similar across ages," Middeldorp added.

The results indicate there are shared genetic factors that affect a range of psychiatric and related traits across a person's lifespan.

Middeldorp said that around 50 per cent of children and adolescents with psychiatric problems, such as attention deficit hyperactivity disorder (ADHD), continue to experience mental disorders as adults, and are at risk of disengaging with their school community among other social and emotional problems.

"Our findings are important as they suggest this continuity between childhood and adult traits is partly explained by genetic risk," the Professor said.

"Individuals at risk of being affected should be the focus of attention and targeted treatment," Middeldorp continued.

"Although the genetic vulnerability is not accurate enough at this stage to make individual predictions about how a person's symptoms will develop over time, it may become so in the future, in combination with other risk factors. And, this may support precision medicine by providing targeted treatments to children at the highest risk of persistent emotional and social problems," Middeldorp added.

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Agencies
August 2,2020

Washington, Aug 2: Children under the age of five have between 10 to 100 times greater levels of genetic material of the coronavirus in their noses compared to older children and adults, a study in JAMA Pediatrics said Thursday.

Its authors wrote this meant that young children might be important drivers of Covid-19 transmission within communities -- a suggestion at odds with the current prevailing narrative.

The paper comes as the administration of US President Donald Trump is pushing hard for schools and daycare to reopen in order to kickstart the economy.

Between March 23 and April 27, researchers carried out nasal swab tests on 145 Chicago patients with mild to moderate illness within one week of symptom onset.

The patients were divided into three groups: 46 children younger than five-years-old, 51 children aged five to 17 years, and 48 adults aged 18 to 65 years.

The team, led by Dr Taylor Heald-Sargent of the Ann & Robert H. Lurie Children's Hospital, observed, "a 10-fold to 100-fold greater amount of SARS-CoV-2 in the upper respiratory tract of young children."

15 countries with the highest number of cases, deaths due to the Covid-19 pandemic

The authors added that a recent lab study had demonstrated that the more viral genetic material was present, the more infectious virus could be grown.

It has also previously been shown that children with high viral loads of the respiratory syncytial virus (RSV) are more likely to spread the disease.

"Thus, young children can potentially be important drivers of SARS-CoV-2 spread in the general population," the authors wrote.

"Behavioral habits of young children and close quarters in school and daycare settings raise concern for SARS-CoV-2 amplification in this population as public health restrictions are eased," they concluded.

The new findings are at odds with the current view among health authorities that young children -- who, it has been well established, are far less likely to fall seriously ill from the virus -- don't spread it much to others either.

However, there has been fairly little research on the topic so far.

One recent study in South Korea found children aged 10 to 19 transmitted Covid-19 within households as much as adults, but children under nine transmitted the virus at lower rates.

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