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May 12: Children suffering from non-respiratory disease symptoms like diarrhea and fever, or those with a history of exposure to the novel coronavirus, should be suspected of having COVID-19, a new study says.

According to the research, published in the journal Frontiers in Pediatrics, gastrointestinal symptoms first suffered by some children hints at potential infection with SARS-CoV-2 through the digestive tract.

"This case series is the first report to describe the clinical features of COVID-19 with non-respiratory symptoms as the first manifestation in children," the scientists from Tongji Hospital in China wrote in the study.

They explained that the gastrointestinal symptoms could be arising since the type of receptors in lung cells targeted by the virus can also be found in the intestines.

Most children are only mildly affected by COVID-19, and the few severe cases often have underlying health issues, the researchers said.

"It is easy to miss its diagnosis in the early stage, when a child has non-respiratory symptoms, or suffers from another illness," said study co-author Wenbin Li, who works at the Department of Pediatrics, Tongji Hospital.

"Based on our experience of dealing with COVID-19, in regions where this virus is epidemic, children suffering from digestive tract symptoms, especially with fever and/or a history of exposure to this disease, should be suspected of being infected with this virus," Li said.

In the study, the scientists described the clinical features of children admitted to hospital with non-respiratory symptoms, who were subsequently diagnosed with pneumonia and COVID-19.

"These children were seeking medical advice in the emergency department for unrelated problems, for example, one had a kidney stone, another a head trauma," Li said.

The study noted that all the children had pneumonia, which was confirmed by chest X-ray scan before or soon after admission.

These children were then confirmed to have COVID-19.

While their COVID-19 symptoms were initially mild or relatively hidden before their hospital admission, four out of the five cases had digestive tract symptoms as the first manifestation of this disease, the researchers said.

Li hopes that doctors will use the findings to quickly diagnose and isolate patients with similar symptoms, which may aid early treatment and reduce transmission.

According to the researchers, the children's gastrointestinal symptoms, which have also been recorded in adult patients, could be an additional route of infection.

"The gastrointestinal symptoms experienced by these children may be related to the distribution of receptors and the transmission pathway associated with COVID-19 infection in humans," Li explained.

Since the virus infects people via the ACE2 receptor, which can be found in certain cells in the lungs as well as the intestines, COVID-19 might infect patients not only through the respiratory tract in the form of air droplets, but also through the digestive tract by contact or fecal-oral transmission, the study noted.

While COVID-19 tests can occasionally produce false positive readings, Li said all the five children assessed in the study were infected with the disease.

However, he cautioned that more research is needed to confirm their findings.

"We report five cases of COVID-19 in children showing non-respiratory symptoms as the first manifestation after admission to hospital. The incidence and clinical features of similar cases needs further study in more patients," he said.

Bengaluru, Jan 10: Chief minister BS Yediyurappa said on Thursday he might not attend the World Economic Forum (WEF) meeting in Davos, Switzerland, and would most likely visit Delhi this weekend for discussions on the pending cabinet expansion.

He was expected to join Union ministers Piyush Goyal and Mansukh Mandaviya, chief ministers Amarinder Singh (Punjab) and Kamal Nath (Madhya Pradesh) and over 100 Indian CEOs at WEF’s 50th annual gathering on January 21-24.

“Mostly, I may not go for Davos (meet),” he told reporters on Thursday. Last week, he had said he was not keen on travelling to the Swiss town but was considering it as some chief ministers’ attendance was required at the high-profile event.

Eleven Congress-JD(S) turncoats, who contested the bypolls on BJP tickets and won, reportedly pressured Yediyurappa to take a decision on cabinet expansion before the now-uncertain Davos trip; it was even suggested that he should simply cancel the trip. The newly elected BJP MLAs are widely expected to be inducted as ministers. But officials in the Chief Minister’s Office (CMO) said his disinclination to travel had nothing to do with the cabinet exercise.

“It’s mainly because of his health. That place (Davos) has got temperature of minus 4-6 degrees and it will be quite tedious for Yediyurappa at the age of 76,” one official said. BJP functionaries, however, claimed that he was wary of taking a trip amid tensions in the party. “The new MLAs have been breathing down Yediyurappa’s neck. They have pushed him into a corner, demanding that he complete cabinet expansion before going anywhere,” a senior functionary said.

On Thursday, the chief minister said he had sought a meeting with party bosses in Delhi. “To discuss cabinet expansion and other important issues, I plan to travel to New Delhi on January 11 or 12. However, I am still waiting for an appointment with the BJP national president and prime minister,” he said.

While Yediyurappa, his additional chief secretary P Ravi Kumar and political adviser MB Maramkal may not visit Davos, a 10-member delegation from Karnataka, including Jagadish Shettar, is expected to travel. There are reports ministers’ family members might join the delegation.

Mangaluru, Jul 2: As many as 90 persons have tested positive for covid-19 in last 24 hours in Dakshina Kannada district. 

With this, the total number of coronavirus positive cases in the district mounted to 915. 

Out of the 90 positive cases, fifteen persons had returned from Kuwait, Saudi Arabia and Dubai. A BJP MLA, DHO and a pathologist are also among those who infected.